The Animal Resource Center is staffed with specialized personnel in animal care and handling to support research and education activities. The center houses small and large animals in its 7,700 squares feet facility and provides information concerning purchasing, basic husbandry, quarantine, and veterinary medical care of laboratory animals.
The center also provides technical assistance and advice dealing with animal species used for investigation and supports the research programs by making readily available animals, materials and animal husbandry supplies.
The center is equipped with specialized areas to provide the following services: necropsy, stock and treatment, quarantine, bedding, cage washing and storage. The facilities also include an experimental surgery area with surgical, scrub, sterilizing, and recovery rooms.
- Application for Protocol Approval Involving Laboratory Animal Use 2013-12-12
- Modification Request Form.2013.12.12
- Rodent Breeding and Weaning Supplement (IACUC)
The Behavioral Testing Facility was created to facilitate the development of neuroscience research at the Universidad Central del Caribe recognizing the importance of behavioral testing. The facility has two mayor components: A) the equipment infrastructure and B) the technical support division. The facility offers equipment for remote behavior visualization (RBV).
Biomedical Proteomic Facility
The mission of the facility is to accelerate discovery by giving UCC investigators access to cutting edge technologies in proteomics and in mass spectrometry. The facility stimulates the use of 2D gels and protein analysis, via the software PD-Quest, by the faculty. The aim is to provide separation and mass spectrometry techniques for the quantitative analysis of the proteome. One major objective is to identify disease and other relevant biological markers.
Common Instrumentation and Technical Support Unit
Is a core area housing major equipment such as ultracentrifuges, freezers, spectrophotometers, gamma counters, etc, as well as the centralized cell culture facility. The unit fosters equipment sharing, centralizes maintenance of equipment and provides repair for the equipment of all the projects.
The DMSRSU provides study design, data management, quality assurance, and statistical analysis support for UCC researchers. The DMSRSU has a strong infrastructure which includes the following subunits: Data Abstraction and Management; Data Entry; Quality Control; Data Analysis and Consultant; and Administrative and Computer Systems. Each of these subunits consists of experienced professionals readily available to assist researchers and to provide data management and statistical research support to investigators. In addition, the DMSRSU counts on a highly experienced and reliable consulting team.
HIV and Substance of Abuse Laboratory Core
The laboratory supports research in the areas of HIV/AIDS and substances of abuse. Specialized facilities are made available to researchers for scientific studies in fields of immunology, drugs of abuse, HIV/AIDS and related infectious diseases. The core lab provides researchers with assays for nucleic acids detection, virus genotyping, flow cytometric phenotyping, lymphocyte proliferation, cytotoxic and non-cytotoxic activity, cytokine and chemokine determinations, and drugs of abuse quantification.
The immunocytochemistry laboratory specializes in the qualitative identification and localization of cells bearing selective markers by employing specific antibodies to these molecules.
Neuronal Glia Culture Facility
The goal of the facility is to assist UCC investigators in the use of cultured neurons, glias and organotypic cultures. The cultures are used for patch clamping after in vitro treatments with drugs of addiction or inhibitors and for in vitro models of neurodegenerative diseases. The core facility consists of a coordinator and a technician. Neuronal cultures are prepared from fetal cortex, hippocampus or astrocytes from cerebral cortex.
Optical Imaging Facility
The facility offers microscope-based systems that allow the assessment of cellular responses, such as calcium signaling with fast temporal resolution. The facility offers 1) Confocal imaging services; 2) Brightfield, darkfield, phase contrast, Nomarski and epi-fluorescence imaging; 3) High spatial and temporal resolution imaging, 4) Collection of serial sections (Deconvolution capabilities) and 5) Morphometric analysis.
Protein and Nucleic Acid Core Facility
The Protein and Nucleic Acid Core Facility (PNACF) aids in the transition from classical to molecular analysis of the problems being addressed by faculty members. PNACF focuses on faculty training, seminars, training on specialized molecular biology techniques, protein expression and protein purification and characterization.Krishna Baksi, Ph.D. firstname.lastname@example.org
Transmission Electron Microscopy Laboratory
The TEM laboratory provides access to ultrastructural analysis of biological specimens via a Jeol 100 CX transmission electron microscope. The TEM is equipped with AMT 4 MP digital camera to facilitate image acquisition and 3D reconstruction from serial sections. In addition, to conventional EM procedures of in situ and cell culture specimens the laboratory also offers immunogold labeling and the visualization of fluorescent dyes after photoconversion.